Keytruda (pembrolizumab) is an immunotherapy drug used to treat various types of cancer

 Keytruda (pembrolizumab) is an immunotherapy drug used to treat various types of cancer. It is a monoclonal antibody that works by targeting the PD-1 (programmed death receptor-1) pathway, helping the immune system recognize and attack cancer cells.

Uses of Keytruda



Keytruda is FDA-approved for treating:

  • Non-small cell lung cancer (NSCLC)
  • Melanoma
  • Head and neck squamous cell carcinoma
  • Hodgkin lymphoma
  • Bladder cancer
  • Colorectal cancer (with microsatellite instability-high or mismatch repair deficiency)
  • Cervical cancer
  • Other cancers with specific genetic markers

How It Works

Cancer cells can evade immune system attacks by binding to PD-1 on T cells, effectively "turning off" the immune response. Keytruda blocks PD-1, allowing the immune system to detect and destroy cancer cells more effectively.

Administration & Dosage

  • Given as an intravenous (IV) infusion
  • Typically administered every 3 to 6 weeks, depending on the condition

Common Side Effects

  • Fatigue
  • Nausea
  • Rash
  • Diarrhea
  • Cough
  • Immune-related side effects (e.g., inflammation of the lungs, liver, intestines, or thyroid)

Cost & Availability

Keytruda is an expensive drug, often costing thousands of dollars per dose. Insurance coverage, manufacturer assistance programs, and clinical trials may help reduce costs.

Would you like information on a specific aspect, such as side effects, clinical trials, or pricing?

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